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>   home   >   Products   >   Primary Antibodies   >   MEKK6 Antibody (C-term)   

MEKK6 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MEKK6 Antibody (C-term) AP7912a
    The anti-MEKK6 Pab (Cat. #AP7912a) is used in Western blot to detect MEKK6 in NIH3T3 cell lysate.
  • IHC-P - MEKK6 Antibody (C-term) AP7912a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95382
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 142596 Da
Antigen Region 1028-1058 aa
Additional Information
Gene ID 9064
Other Names Mitogen-activated protein kinase kinase kinase 6, Apoptosis signal-regulating kinase 2, MAP3K6, ASK2, MAPKKK6, MEKK6
Target/Specificity This MEKK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1028-1058 amino acids from the C-terminal region of human MEKK6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMEKK6 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP3K6
Synonyms ASK2, MAPKKK6, MEKK6
Function Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.
Citations ( 0 )


Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MEKK6 activates the JNK, but not ERK or p38 kinase pathways.


Wang, X.S., et al., Biochem. Biophys. Res. Commun. 253(1):33-37 (1998).

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$ 295.00
$ 99.00
Cat# AP7912a
(40 western blots)
Availability: In Stock
Bulk Size
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