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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MLK2 Antibody (C-term)   

MLK2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MLK2 Antibody (C-term) AP7920a
    The anti-MLK2 Pab (Cat. #AP7920a) is used in Western blot to detect MLK2 in transfected COS7 cell lysate. Data is kindly provided by Drs. M.K. Barthwal and A. Rana from Texas A&M University, Health Science Center (Temple, TX).
  • IHC-P - MLK2 Antibody (C-term) AP7920a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02779
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 103694 Da
Antigen Region 628-659 aa
Additional Information
Gene ID 4294
Other Names Mitogen-activated protein kinase kinase kinase 10, Mixed lineage kinase 2, Protein kinase MST, MAP3K10, MLK2, MST
Target/Specificity This MLK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 628-659 amino acids from the C-terminal region of human MLK2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMLK2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MAP3K10
Synonyms MLK2, MST
Function Activates the JUN N-terminal pathway.
Tissue Location Expressed in brain and skeletal muscle.
Research Areas
Citations ( 0 )


MLK2 is a member of the serine/threonine kinase family. This kinase has been shown to activate MAPK8/JNK and MKK4/SEK1, and this kinase itself can be phoshorylated, and thus activated by JNK kinases. This kinase functions preferentially on the JNK signaling pathway, and is reported to be involved in nerve growth factor (NGF) induced neuronal apoptosis.


Dorow, D.S., et al., Eur. J. Biochem. 234(2):492-500 (1995).
Katoh, M., et al., Oncogene 10(7):1447-1451 (1995).
Dorow, D.S., et al., Eur. J. Biochem. 213(2):701-710 (1993).

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$ 295.00
$ 99.00
Cat# AP7920a
(40 western blots)
Availability: In Stock
Bulk Size
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