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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BDNF Antibody (C-term)   

BDNF Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BDNF Antibody (C-term) AP7979B
    All lanes : Anti-BDNF Antibody (C-term) at 1:1000 dilution Lane 1: human cerebellum lysate Lane 2: U-87 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 28 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - BDNF Antibody (C-term) AP7979B
    Western blot analysis of BDNF Antibody (C-term)(Cat.#AP7979b) in CEM cell line lysates (35ug/lane). BDNF (arrow) was detected using the purified Pab.
  • IHC-P - BDNF Antibody (C-term) AP7979B
    Formalin-fixed and paraffin-embedded human brain reacted with BDNF Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • IF - BDNF Antibody (C-term) AP7979B
    Confocal immunofluorescent analysis of BDNF Antibody (C-term)(Cat#AP7979b) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
  • FC - BDNF Antibody (C-term) AP7979B
    Flow cytometric analysis of CEM cells using BDNF Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23560
Other Accession P23363, P14082, P21237, Q95106, Q0EAB7
Reactivity Human
Predicted Bovine, Mouse, Pig, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27818 Da
Antigen Region 206-236 aa
Additional Information
Gene ID 627
Other Names Brain-derived neurotrophic factor, BDNF, Abrineurin, BDNF
Target/Specificity This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBDNF Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Cellular Location Secreted.
Tissue Location Brain. Highly expressed in hippocampus, amygdala, cerebral cortex and cerebellum. Also expressed in heart, lung, skeletal muscle, testis, prostate and placenta
Research Areas
Citations (0)

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BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this protein is reduced in both Alzheimer's and Huntington disease patients. This protein may play a role in the regulation of stress response and in the biology of mood disorders.


Jiang,H., Clin. Chim. Acta 400 (1-2), 3-7 (2009)
Liu,L., Psychiatr. Genet. 18 (6), 267-274 (2008)
Dmitrzak-Weglarz,M., Pharmacogenomics 9 (11), 1595-1603 (2008)

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$ 295.00
$ 99.00
Cat# AP7979B
(40 western blots)
Availability: In Stock
Bulk Size
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