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APOH Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP7989b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP7989b-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
APOH Antibody (C-term) - Product info | |
| Application | WB, IF, FC
|
| Primary Accession | P02749 |
| Other Accession | P17690 |
| Reactivity | Human |
| Predicted | Bovine |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 38298 Da |
APOH Antibody (C-term) - Additional info | |
| Gene ID 350 | |
| Other Names APOH; B2G1; Beta-2-glycoprotein 1; APC inhibitor; Activated protein C-binding protein; Anticardiolipin cofactor; Apolipoprotein H; Beta-2-glycoprotein I | |
| Target/Specificity This APOH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acid 315-345 from the C-terminal region of human APOH. | |
| Dilution WB~~1:100~500WB~~1:1000 IF~~1:10~50 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions APOH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
APOH Antibody (C-term) - Protein Information | |
| Name APOH | |
| Synonyms B2G1 | |
| Function Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells | |
| Cellular Location Secreted. | |
| Tissue Location Expressed by the liver and secreted in plasma. | |
APOH Antibody (C-term) - Related products
AP7989b: APOH Antibody (C-term)
BP7989a: APOH Antibody (N-term) Blocking Peptide
APOH Antibody (C-term) - Application data
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Western blot analysis of APOH Antibody (C-term) (Cat. #AP7989b) in MDA-MB231 cell line lysates (35ug/lane). APOH (arrow) was detected using the purified Pab.
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Confocal immunofluorescent analysis of APOH Antibody (C-term) (Cat#AP7989b) with MDA-MB231 cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
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APOH Antibody (C-term) (Cat. #AP7989b) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
APOH Antibody (C-term) - Research Areas
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BACKGROUND
Apolipoprotein H has been implicated in a variety of physiologic pathways including lipoprotein metabolism, coagulation, and the production of antiphospholipid autoantibodies. APOH may be a required cofactor for anionic phospholipid binding by the antiphospholipid autoantibodies found in sera of many patients with lupus and primary antiphospholipid syndrome, but it does not seem to be required for the reactivity of antiphospholipid autoantibodies associated with infections.
REFERENCES
Davila, S., et al. Genes Immun. 11(3):232-238(2010) Zhang, C., et al. Clin. Chim. Acta 411 (5-6), 395-399 (2010) Suresh, S., et al. FEBS J. 277(4):951-963(2010)
