|Application ||IHC-P, E|
|Calculated MW||66116 Da|
|Other Names||Phenylalanine--tRNA ligase beta subunit, Phenylalanyl-tRNA synthetase beta subunit, PheRS, FARSB, FARSLB, FRSB|
|Target/Specificity||This FARSB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human FARSB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FARSB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
FARSB is a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA.
Yu,X.Y., Bioorg. Med. Chem. Lett. 14 (5), 1339-1342 (2004)
Vasil'eva,I.A., Biochemistry Mosc. 69 (2), 143-153 (2004)
Moor,N., Biochemistry 42 (36), 10697-10708 (2003)
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