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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   BRD2 Antibody (Center)   

BRD2 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - BRD2 Antibody (Center) AP8049c
    BRD2-Q185 (Cat.#AP8049c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the BRD2 antibody detected the BRD2 protein (arrow).
  • WB - BRD2 Antibody (Center) AP8049c
    Western blot analysis of BRD2 (arrow) using rabbit polyclonal BRD2 Antibody (Center) (Cat.#AP8049c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the BRD2 gene (Lane 2) (Origene Technologies).
  • IHC-P - BRD2 Antibody (Center) AP8049c
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P25440
Other Accession Q6MGA9, Q7JJ13, Q32S26
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 88061 Da
Antigen Region 170-200 aa
Additional Information
Gene ID 6046
Other Names Bromodomain-containing protein 2, O2711, Really interesting new gene 3 protein, BRD2, KIAA9001, RING3
Target/Specificity This BRD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-200 amino acids from the Central region of human BRD2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBRD2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BRD2
Synonyms KIAA9001, RING3
Function May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.
Cellular Location Nucleus. Note=Detected on chromatin and nucleosomes
Research Areas
Citations (0)

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BRD2 is a mitogen-activated kinase which localizes to the nucleus. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3 but sequence comparison suggests that the protein is not involved in the immune response. Homology to the Drosophila gene female sterile homeotic suggests that this human protein may be part of a signal transduction pathway involved in growth control.


Pal, D.K., et al., Am. J. Hum. Genet. 73(2):261-270 (2003).
Crowley, T.E., et al., Mol. Endocrinol. 16(8):1727-1737 (2002).
Denis, G.V., et al., Cell Growth Differ. 11(8):417-424 (2000).
Taniguchi, Y., et al., Genomics 51(1):114-123 (1998).
Thorpe, K.L., et al., Immunogenetics 44(5):391-396 (1996).

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$ 295.00
$ 99.00
Cat# AP8049c
(40 western blots)
Availability: In Stock
Bulk Size
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