|Application ||WB, E|
|Calculated MW||21142 Da|
|Antigen Region||80-110 aa|
|Other Names||Nucleoside diphosphate kinase 6, NDK 6, NDP kinase 6, Inhibitor of p53-induced apoptosis-alpha, IPIA-alpha, nm23-H6, NME6|
|Target/Specificity||This NME6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 80-110 amino acids from the N-terminal region of human NME6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NME6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.|
|Tissue Location||Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
NME6 plays a major role in the synthesis of nucleoside triphosphates other than ATP. It is an inhibitor of p53-induced apoptosis. NME6 is expressed at a moderately low level in many tissues, most abundantly in kidney, prostate, ovary, intestine, and spleen.
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002).
Mehus, J.G., et al., Hum. Genet. 104(6):454-459 (1999).
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.