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PACSIN2 Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP8088b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP8088b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 1
- Reviews
- Protocols
- Backgrounds
PACSIN2 Antibody (C-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q9UNF0 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 55739 Da |
PACSIN2 Antibody (C-term) - Additional info | |
| Gene ID 11252 | |
| Other Names PACSIN2; Protein kinase C and casein kinase substrate in neurons protein 2 | |
| Target/Specificity This PACSIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 349~379 amino acids from the C-terminal region of human PACSIN2. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions PACSIN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
PACSIN2 Antibody (C-term) - Protein Information | |
| Name PACSIN2 | |
| Function May play a role in endocytosis. | |
| Cellular Location Cytoplasm (By similarity). Note=Endocytic vesicle-like cytoplasmic distribution (By similarity) | |
| Tissue Location Widely expressed. | |
PACSIN2 Antibody (C-term) - Related products
AP8088b: PACSIN2 Antibody (C-term)
AP8088c: PACSIN2 Antibody (Center)
RI13777: PACSIN2 predesign siRNA
DC02314: Human PACSIN2 cDNA Clone
LY11673a: PACSIN2 Over-expression Lysate
PACSIN2 Antibody (C-term) - Application data
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The anti-PACSIN2 Pab (Cat. #AP8088b) is used in Western blot to detect PACSIN2 in T-47D cell lysate (Lane 1) and mouse brain tissue lysate (Lane 2).
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
PACSIN2 Antibody (C-term) - Research Areas
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BACKGROUND
PACSIN may play a role in vesicle formation and transport. This protein homo- and hetero-aggregates with other PACSINs. It also binds dynamin 1, synaptojanin, synapsin 1 and the neural Wiskott-Aldrich syndrome protein (N-WASP). The protein exhibits a cvesicle-like cytoplasmic distribution and is ubiquitously expressed. PACSIN is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). The protein contains 1 FCH domain and 1 SH3 domain.
REFERENCES
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). Wiemann, S., et al., Genome Res. 11(3):422-435 (2001). Ritter, B., et al., FEBS Lett. 454(3):356-362 (1999). Dunham, I., et al., Nature 402(6761):489-495 (1999).
