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Natriuretic Peptide Receptor A Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - Natriuretic Peptide Receptor A Antibody (N-term) AP8111A
    Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Natriuretic Peptide Receptor A (NPR1/ANPA) antibody (N-term) (Cat. #AP8111a), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16066
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 118919 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 4881
Other Names Atrial natriuretic peptide receptor 1, Atrial natriuretic peptide receptor type A, ANP-A, ANPR-A, NPR-A, Guanylate cyclase A, GC-A, NPR1, ANPRA
Target/Specificity This Natriuretic Peptide Receptor A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human Natriuretic Peptide Receptor A.
Dilution IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNatriuretic Peptide Receptor A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NPR1
Synonyms ANPRA
Function Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
Cellular Location Membrane; Single-pass type I membrane protein
Research Areas
Citations ( 0 )


ANPA is a receptor for atrial natriuretic peptide. It exhibits guanylate cyclase activity on binding of ANF. There seem to be at least three ANP receptors: two with guanylate cyclase activity (ANPA and ANPB) and one (ANPC) which is probably responsible for the clearance of ANP from the circulation without a role in signal transduction. This Type I membrane protein belongs to the adenylyl cyclase class-4/guanylyl cyclase family and contains 1 protein kinase-like domain.


Takahashi, Y., et al., Biochem. Biophys. Res. Commun. 246(3):736-739 (1998). Pardhasaradhi, K., et al., Cell. Mol. Neurobiol. 14(1):1-7 (1994). Lowe, D.G., et al., EMBO J. 8(5):1377-1384 (1989).

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$ 295.00
$ 99.00
Cat# AP8111A
(40 western blots)
Availability: In Stock
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