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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ITPKA Antibody (C-term)   

ITPKA Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ITPKA Antibody (C-term) AP8166b
    All lanes : Anti-ITPKA Antibody (C-term) at 1:1000 dilution Lane 1: human brain lysate Lane 2: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 51 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - ITPKA Antibody (C-term) AP8166b
    Western blot analysis of hITPKA-E360 (Cat.# AP8166b) in K562 cell line and mouse lung tissue lysates (35ug/lane). ITPKA (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23677
Other Accession NP_002211
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51009 Da
Antigen Region 345-375 aa
Additional Information
Gene ID 3706
Other Names Inositol-trisphosphate 3-kinase A, Inositol 1, 5-trisphosphate 3-kinase A, IP3 3-kinase A, IP3K A, InsP 3-kinase A, ITPKA
Target/Specificity This ITPKA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 345-375 amino acids from the C-terminal region of human ITPKA.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITPKA Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)

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ITPKA regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of the inositol 1,4,5-trisphosphate 3-kinase is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. It is also a substrate for the cyclic AMP-dependent protein kinase, calcium/calmodulin- dependent protein kinase II, and protein kinase C in vitro. ITPKA and ITPKB are 68% identical in the C-terminus region.


Gonzalez, B., et al., Mol. Cell 15(5):689-701 (2004).
Mishra, J., et al., Biophys. J. 83(3):1298-1316 (2002).
Schell, M.J., et al., J. Biol. Chem. 276(40):37537-37546 (2001).
Communi, D., et al., EMBO J. 16(8):1943-1952 (1997).
Woodring, P.J., et al., J. Biol. Chem. 272(48):30447-30454 (1997).

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$ 295.00
$ 99.00
Cat# AP8166b
(40 western blots)
Availability: In Stock
Bulk Size
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