- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||52249 Da|
|Antigen Region||427-457 aa|
|Other Names||Choline kinase alpha, CK, CHETK-alpha, Ethanolamine kinase, EK, CHKA, CHK, CKI|
|Target/Specificity||This Choline kinase alpha (CHK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 427-457 amino acids from the C-terminal region of human Choline kinase alpha (CHK).|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Choline kinase alpha (CHK) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.|
Provided below are standard protocols that you may find useful for product applications.
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. Choline kinase alpha is the initial enzyme in the sequence and may play a regulatory role. This protein also catalyzes the phosphorylation of ethanolamine. The antibody for this protein recognizes both isoforms.
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