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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTP epsilon Antibody (C-term)   

PTP epsilon Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTP epsilon Antibody (C-term) AP8416a
    Abgent invites you to submit your data (IHC, IF, IP, WB, FC) using this product. We will award you credits, 50% of the cost you paid, for future purchases. For availability of this promotion please contact us at
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P23469
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 80642 Da
Antigen Region 558-589 aa
Additional Information
Gene ID 5791
Other Names Receptor-type tyrosine-protein phosphatase epsilon, Protein-tyrosine phosphatase epsilon, R-PTP-epsilon, PTPRE
Target/Specificity This PTP epsilon antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-589 amino acids from the C-terminal region of human PTP epsilon.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTP epsilon Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function (By similarity).
Cellular Location Isoform 1: Cell membrane; Single-pass type I membrane protein Isoform 3: Cytoplasm.
Tissue Location Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells)
Research Areas
Citations ( 0 )


PTPepsilon is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of the gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.


Toledano-Katchalski, H., et al., Mol. Cell. Biol. 23(15):5460-5471 (2003).
Blanchetot, C., et al., J. Biol. Chem. 277(49):47263-47269 (2002).
Wabakken, T., et al., Scand. J. Immunol. 56(3):276-285 (2002).
Wabakken, T., et al., Scand. J. Immunol. 56(2):195-203 (2002).
Tanuma, N., et al., J. Biol. Chem. 275(36):28216-28221 (2000).

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$ 295.00
$ 99.00
Cat# AP8416a
(40 western blots)
Availability: In Stock
Bulk Size
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