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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PTPD1 Antibody (Center)   

PTPD1 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PTPD1 Antibody (Center) AP8424a
    Anti-PTPD1 Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 133 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • IHC-P - PTPD1 Antibody (Center) AP8424a
    Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PTPD1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q16825
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 133281 Da
Antigen Region 751-780 aa
Additional Information
Gene ID 11099
Other Names Tyrosine-protein phosphatase non-receptor type 21, Protein-tyrosine phosphatase D1, PTPN21, PTPD1
Target/Specificity This PTPD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human PTPD1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPTPD1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PTPN21
Synonyms PTPD1
Cellular Location Cytoplasm, cytoskeleton.
Research Areas
Citations ( 0 )


PTPD1 is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal domain, similar to cytoskeletal- associated proteins including band 4.1, ezrin, merlin, and radixin. This PTP was shown to specially interact with BMX/ETK, a member of Tec tyrosine kinase family characterized by a multimodular structures including PH, SH3, and SH2 domains. The interaction of this PTP with BMX kinase was found to increase the activation of STAT3, but not STAT2 kinase. Studies of the similar gene in mice suggested the possible roles of this PTP in liver regeneration and spermatogenesis.


Jui, H.Y., et al., J. Biol. Chem. 275(52):41124-41132 (2000).
Tokuchi, H., et al., Int J Urol 6(11):572-577 (1999).
Higashitsuji, H., et al., Oncogene 10(2):407-414 (1995).
Moller, N.P., et al., Proc. Natl. Acad. Sci. U.S.A. 91(16):7477-7481 (1994).

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$ 295.00
$ 99.00
Cat# AP8424a
(40 western blots)
Availability: In Stock
Bulk Size
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