- CITATIONS: 2
|Application ||WB, IHC-P, E|
|Calculated MW||10085 Da|
|Antigen Region||59-87 aa|
|Other Names||C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, PAT 4641, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3|
|Target/Specificity||This CCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the C-terminal region of human CCL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||G0S19-1, MIP1A, SCYA3|
|Function||Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).|
Provided below are standard protocols that you may find useful for product applications.
Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.
Hirashima,M., et.al., DNA Seq. 3 (4), 203-212 (1992) Blum,S., et.al., DNA Cell Biol. 9 (8), 589-602 (1990)
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