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CCL3 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CCL3 Antibody (C-term) AP8527b
    Western blot analysis of CCL3 Antibody (C-term) (Cat. #AP8527b) in mouse liver tissue lysates (35ug/lane). CCL3 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - CCL3 Antibody (C-term) AP8527b
    Formalin-fixed and paraffin-embedded human tonsil tissue reacted with CCL3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • SPECIFICATION
  • CITATIONS: 2
  • PROTOCOLS
  • BACKGROUND
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession P10147
Other Accession P16619
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 10085 Da
Antigen Region 59-87 aa
Additional Information
Gene ID 6348
Other Names C-C motif chemokine 3, G0/G1 switch regulatory protein 19-1, Macrophage inflammatory protein 1-alpha, MIP-1-alpha, PAT 4641, SIS-beta, Small-inducible cytokine A3, Tonsillar lymphocyte LD78 alpha protein, MIP-1-alpha(4-69), LD78-alpha(4-69), CCL3, G0S19-1, MIP1A, SCYA3
Target/Specificity This CCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-87 amino acids from the C-terminal region of human CCL3.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCL3
Synonyms G0S19-1, MIP1A, SCYA3
Function Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose- dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).
Cellular Location Secreted.
Research Areas
Citations ( 0 )

Background

Macrophage inflammatory protein-1 is a so-called monokine that is involved in the acute inflammatory state in the recruitment and activation of polymorphonuclear leukocytes.

References

Hirashima,M., et.al., DNA Seq. 3 (4), 203-212 (1992) Blum,S., et.al., DNA Cell Biol. 9 (8), 589-602 (1990)

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$ 182.50
$ 70.00
Cat# AP8527b
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