- CITATIONS: 1
|Application ||WB, IHC-P, FC, E|
|Calculated MW||41466 Da|
|Antigen Region||281-309 aa|
|Other Names||Alpha-2-macroglobulin receptor-associated protein, Alpha-2-MRAP, Low density lipoprotein receptor-related protein-associated protein 1, RAP, LRPAP1, A2MRAP|
|Target/Specificity||This LRPAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-309 amino acids from the C-terminal region of human LRPAP1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LRPAP1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Molecular chaperone for LDL receptor-related proteins that may regulate their ligand binding activity along the secretory pathway.|
|Cellular Location||Rough endoplasmic reticulum lumen. Endoplasmic reticulum-Golgi intermediate compartment lumen. Golgi apparatus, cis-Golgi network. Golgi apparatus lumen. Endosome lumen. Cell surface. Note=May be associated with receptors at the cell surface.|
Provided below are standard protocols that you may find useful for product applications.
LRPAP1 interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330.
Lisi,S., et.al., J. Endocrinol. Invest. 30 (10), 839-843 (2007)
Vertegaal,A.C., et.al., Mol. Cell Proteomics 5 (12), 2298-2310 (2006)
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