|Application ||WB, FC, IHC-P, IF, E|
|Other Accession||P05419, P62155, P62161, P62160, P62204, P62152, Q6PI52, P62149, O16305, P62157, NP_008819, Q6YNX6|
|Predicted||Bovine, C.Elegans, Chicken, Zebrafish, Drosophila, Mouse, Rabbit, Rat, Xenopus|
|Calculated MW||16838 Da|
|Antigen Region||107-132 aa|
|Other Names||Calmodulin, CaM, CALM1, CALM, CAM, CAM1|
|Target/Specificity||This CALM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 107-132 amino acids from the C-terminal region of human CALM1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CALM1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CALM, CAM, CAM1|
|Function||Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.|
|Cellular Location||Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules|
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Provided below are standard protocols that you may find useful for product applications.
CALM1 is a member of the EF-hand calcium-binding protein family.Calmodulin mediates the control of a large number of enzymes and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. Together with CEP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis.
Zhao,D., et.al., Zhonghua Yi Xue Za Zhi 88 (35), 2452-2456 (2008)
Martins-de-Souza,D., et.al., J. Neural Transm. 116 (3), 275-289 (2009)
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