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HPD Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | P32754 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44934 Da |
| Antigen Region | 92-121 aa |
| Gene ID | 3242 |
|---|---|
| Other Names | 4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase, HPD, PPD |
| Target/Specificity | This HPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the N-terminal region of human HPD. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HPD Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HPD |
|---|---|
| Synonyms | PPD |
| Function | Catalyzes the conversion of 4-hydroxyphenylpyruvic acid to homogentisic acid, one of the steps in tyrosine catabolism. |
| Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P32755}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:P32755}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32755}. Golgi apparatus membrane {ECO:0000250|UniProtKB:P32755}; Peripheral membrane protein {ECO:0000250|UniProtKB:P32755} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
HPD is an enzyme in the catabolic pathway of tyrosine. This protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate.
References
Item,C.B., et.al., Mol. Genet. Metab. 91 (4), 379-383 (2007)
Wistow,G., et.al., Mol. Vis. 8, 171-184 (2002)
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