|Application ||WB, IHC-P, E|
|Calculated MW||44934 Da|
|Antigen Region||255-284 aa|
|Other Names||4-hydroxyphenylpyruvate dioxygenase, 4-hydroxyphenylpyruvic acid oxidase, 4HPPD, HPD, HPPDase, HPD, PPD|
|Target/Specificity||This HPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-284 amino acids from the C-terminal region of human HPD.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HPD Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Key enzyme in the degradation of tyrosine.|
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Provided below are standard protocols that you may find useful for product applications.
HPD is an enzyme in the catabolic pathway of tyrosine. This protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate.
Item,C.B., et.al., Mol. Genet. Metab. 91 (4), 379-383 (2007)
Wistow,G., et.al., Mol. Vis. 8, 171-184 (2002)
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