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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   ZMYND11 Antibody (N-term)   

ZMYND11 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ZMYND11 Antibody (N-term) AP8592a
    Western blot analysis of ZMYND11 Antibody (N-term) (Cat. #AP8592a) in mouse brain tissue lysates (35ug/lane). ZMYND11 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15326
Other Accession Q8R5C8
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 70963 Da
Antigen Region 152-180 aa
Additional Information
Gene ID 10771
Other Names Zinc finger MYND domain-containing protein 11, Adenovirus 5 E1A-binding protein, Bone morphogenetic protein receptor-associated molecule 1, Protein BS69, ZMYND11, BRAM1, BS69
Target/Specificity This ZMYND11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-180 amino acids from the N-terminal region of human ZMYND11.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsZMYND11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ZMYND11
Synonyms BRAM1, BS69
Function Chromatin reader that specifically recognizes and binds histone H3.3 trimethylated at 'Lys-36' (H3.3K36me3) and regulates RNA polymerase II elongation. Does not bind other histone H3 subtypes (H3.1 or H3.2) (By similarity). Colocalizes with highly expressed genes and functions as a transcription corepressor by modulating RNA polymerase II at the elongation stage. Acts as a tumor-suppressor by repressing a transcriptional program essential for tumor cell growth.
Cellular Location Nucleus. Chromosome. Note=Associates with chromatin and mitotic chromosomes
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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ZMYND11 is first identified by its ability to bind the adenovirus E1A protein. The protein localizes to the nucleus. It functions as a transcriptional repressor, and expression of E1A inhibits this repression.


Yu,B., Shao,Y.,, Exp. Cell Res. 315 (20), 3543-3553 (2009)
Kurozumi,K.,, Genes Cells 3 (4), 257-264 (1998)

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Cat# AP8592a
(40 western blots)
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