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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   JAKMIP1 Antibody (Center)   

JAKMIP1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - JAKMIP1 Antibody (Center) AP8685c
    Western blot analysis of JAKMIP1 Antibody (Center) (Cat. #AP8685c) in 293 cell line lysates (35ug/lane). JAKMIP1 (arrow) was detected using the purified Pab.
  • IHC-P - JAKMIP1 Antibody (Center) AP8685c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with JAKMIP1 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q96N16
Other Accession Q3SWS9, Q8BVL9, A6QR54
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 73209 Da
Antigen Region 270-297 aa
Additional Information
Gene ID 152789
Other Names Janus kinase and microtubule-interacting protein 1, GABA-B receptor-binding protein, Multiple alpha-helices and RNA-linker protein 1, Marlin-1, JAKMIP1, GABABRBP, JAMIP1, MARLIN1
Target/Specificity This JAKMIP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-297 amino acids from the Central region of human JAKMIP1.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsJAKMIP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name JAKMIP1
Synonyms GABABRBP, JAMIP1, MARLIN1
Function Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.
Cellular Location Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network. Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells
Tissue Location Predominantly expressed in neural tissues and lymphoid cells (at protein level). Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine.
Research Areas
Citations (0)

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Background

JAKMIP1 associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. It may play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.

References

Jin,J., et.al., Curr. Biol. 14 (16), 1436-1450 (2004)
Steindler,C., et.al., J. Biol. Chem. 279 (41), 43168-43177 (2004)

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Anonymous
2016-08-23 17:15:32
1 2 3 4 5

Species tested
Human,Mouse,Rat
Application tested
WB
Brief protocol
1. Block with 3% skim milk for 1 hour at room temperature. 2. Incubate overnight with Abgent primary antibody 1:1000 in 3% skim milk at 4℃ 3. Wash 5*5 min with TBST. 4. Incubate with HRP-conjugated secondary antibody 1:5000 in 3% skim milk for 1 hour at room temperature. 5. Wash 5*5 min with TBST. 6. Incubate with ECL substrates and expose
$ 295.00
$ 99.00
Cat# AP8685c
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
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