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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MOSC2 Antibody (C-term)   

MOSC2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MOSC2 Antibody (C-term) AP8688B
    Western blot analysis of MOSC2 Antibody (C-term) (Cat. #AP8688b) in Hela cell line lysates (35ug/lane). MOSC2 (arrow) was detected using the purified Pab.
  • IHC-P - MOSC2 Antibody (C-term) AP8688B
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with MOSC2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - MOSC2 Antibody (C-term) AP8688B
    MOSC2 Antibody (C-term) (Cat.#AP8688b) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - MOSC2 Antibody (C-term) AP8688B
    Western blot analysis of MOSC2 (arrow) using rabbit polyclonal MOSC2 Antibody (C-term) (Cat. #AP8688b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the MOSC2 gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q969Z3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38023 Da
Antigen Region 270-300 aa
Additional Information
Gene ID 54996
Other Names Mitochondrial amidoxime reducing component 2, mARC2, 1---, Molybdenum cofactor sulfurase C-terminal domain-containing protein 2, MOSC domain-containing protein 2, Moco sulfurase C-terminal domain-containing protein 2, MARC2, MOSC2
Target/Specificity This MOSC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-300 amino acids from the C-terminal region of human MOSC2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMOSC2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MARC2
Synonyms MOSC2
Function As a component of the benzamidoxime prodrug-converting complex required to reduce N-hydroxylated prodrugs, such as benzamidoxime. Also able to reduce N(omega)-hydroxy-L-arginine (NOHA) and N(omega)-hydroxy-N(delta)-methyl-L-arginine (NHAM) into L-arginine and N(delta)-methyl-L-arginine, respectively.
Cellular Location Mitochondrion outer membrane; Peripheral membrane protein. Peroxisome
Research Areas
Citations (0)

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Catalytic component of the benzamidoxime prodrug-converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex.


Havemeyer,A.,, J. Biol. Chem. 281 (46), 34796-34802 (2006)
Simpson,J.C.,,EMBO Rep. 1 (3), 287-292 (2000)

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$ 295.00
$ 99.00
Cat# AP8688B
(40 western blots)
Availability: In Stock
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