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MC3R Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MC3R Antibody (Center) AP8719c
    Western blot analysis of MC3R Antibody (Center) (Cat. #AP8719c) in K562 cell line lysates (35ug/lane). MC3R (arrow) was detected using the purified Pab.
  • FC - MC3R Antibody (Center) AP8719c
    MC3R Antibody (Center) (Cat. #AP8719c) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P41968
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36043 Da
Antigen Region 86-112 aa
Additional Information
Gene ID 4159
Other Names Melanocortin receptor 3, MC3-R, MC3R
Target/Specificity This MC3R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-112 amino acids from the Central region of human MC3R.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMC3R Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MC3R
Function Receptor for MSH (alpha, beta and gamma) and ACTH. This receptor is mediated by G proteins which activate adenylate cyclase. Required for expression of anticipatory patterns of activity and wakefulness during periods of limited nutrient availability and for the normal regulation of circadian clock activity in the brain.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Brain, placental, and gut tissues.
Research Areas
Citations (0)

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MC3R is a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. This gene maps to the same region as the locus for benign neonatal epilepsy.


Magenis,R.E.,, Mamm. Genome 5 (8), 503-508 (1994)
Konda,Y.,, J. Biol. Chem. 269 (18), 13162-13166 (1994)

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$ 295.00
$ 99.00
Cat# AP8719c
(40 western blots)
Availability: In Stock
Bulk Size
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