CCDC3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | Q9BQI4 |
Other Accession | Q9D6Y1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 30731 Da |
Antigen Region | 195-222 aa |
Gene ID | 83643 |
---|---|
Other Names | Coiled-coil domain-containing protein 3, Fat/vessel-derived secretory protein, Favine, CCDC3 |
Target/Specificity | This CCDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-222 amino acids from the C-terminal region of human CCDC3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CCDC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CCDC3 |
---|---|
Function | Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs (PubMed:25193116). Positively regulates lipid accumulation in adipose cells (By similarity). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q9D6Y1}. |
Tissue Location | Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC) |
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Provided below are standard protocols that you may find useful for product applications.
References
Mural,R.J., et.al., Submitted (05-JUL-2005) Celera Genomics, 45 W. Gude Dr., Rockville,MD 20850, USA
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