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CCDC3 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CCDC3 Antibody (C-term) AP8744b
    Western blot analysis of CCDC3 Antibody (C-term) (Cat. #AP8744b) in mouse bladder tissue lysates (35ug/lane). CCDC3 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - CCDC3 Antibody (C-term) AP8744b
    Formalin-fixed and paraffin-embedded human spleen reacted with CCDC3 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
  • FC - CCDC3 Antibody (C-term) AP8744b
    CCDC3 Antibody (C-term) (Cat. #AP8744b) flow cytometric analysis of WiDr cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
FC, IHC-P, WB, E
Primary Accession Q9BQI4
Other Accession Q9D6Y1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 30731 Da
Antigen Region 195-222 aa
Additional Information
Gene ID 83643
Other Names Coiled-coil domain-containing protein 3, Fat/vessel-derived secretory protein, Favine, CCDC3
Target/Specificity This CCDC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-222 amino acids from the C-terminal region of human CCDC3.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCDC3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CCDC3
Function Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs (PubMed:25193116). Positively regulates lipid accumulation in adipose cells (By similarity).
Cellular Location Secreted {ECO:0000250|UniProtKB:Q9D6Y1}.
Tissue Location Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC)
Research Areas
Citations (0)
citation

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References

Mural,R.J., et.al., Submitted (05-JUL-2005) Celera Genomics, 45 W. Gude Dr., Rockville,MD 20850, USA

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$ 365.00
$ 140.00
Cat# AP8744b
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