|Application ||WB, IHC-P, FC, E|
|Calculated MW||19733 Da|
|Antigen Region||24-50 aa|
|Other Names||Protein Mpv17, MPV17|
|Target/Specificity||This MPV17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 24-50 amino acids from the N-terminal region of human MPV17.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MPV17 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in mitochondria homeostasis. May be involved in the metabolism of reactive oxygen species and control of oxidative phosphorylation and mitochondrial DNA (mtDNA) maintenance.|
|Cellular Location||Mitochondrion inner membrane; Multi- pass membrane protein|
|Tissue Location||Ubiquitous. Expressed in pancreas, kidney, muscle, liver, lung, placenta, brain and heart|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
MPV17 is a mitochondrial inner membrane protein that is implicated in the metabolism of reactive oxygen species.
Iida,R., et.al., J. Biol. Chem. 278 (8), 6301-6306 (2003)
Karasawa,M., et.al., Hum. Mol. Genet. 2 (11), 1829-1834 (1993)
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