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DRD4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DRD4 Antibody (Center) AP8760C
    Western blot analysis of DRD4 Antibody (Center) (Cat. #AP8760c) in mouse heart tissue lysates (35ug/lane). DRD4 (arrow) was detected using the purified Pab.
  • IHC-P - DRD4 Antibody (Center) AP8760C
    Formalin-fixed and paraffin-embedded human brain tissue reacted with DRD4 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - DRD4 Antibody (Center) AP8760C
    DRD4 Antibody (Center) (Cat. #AP8760c) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P21917
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48361 Da
Antigen Region 365-391 aa
Additional Information
Gene ID 1815
Other Names D(4) dopamine receptor, D(2C) dopamine receptor, Dopamine D4 receptor, DRD4
Target/Specificity This DRD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 365-391 amino acids from the Central region of human DRD4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDRD4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DRD4
Function Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).
Cellular Location Cell membrane; Multi-pass membrane protein
Research Areas
Citations ( 0 )


DRD4 is the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease.


Livingstone,C.D.,, Biochem. J. 287 (PT 1), 277-282 (1992)

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$ 295.00
$ 99.00
Cat# AP8760C
(40 western blots)
Availability: In Stock
Bulk Size
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