|Application ||WB, IHC-P, FC, E|
|Calculated MW||35231 Da|
|Antigen Region||12-41 aa|
|Other Names||Deoxyribose-phosphate aldolase, DERA, 2-deoxy-D-ribose 5-phosphate aldolase, Phosphodeoxyriboaldolase, Deoxyriboaldolase, DERA|
|Target/Specificity||This DERA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 12-41 amino acids from the N-terminal region of human DERA.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DERA Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.|
|Cellular Location||Cytoplasm. Cytoplasmic granule. Nucleus. Note=Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.|
|Tissue Location||Mainly expressed in liver, lung and colon.|
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Sgarrella,F., et.al., Comp. Biochem. Physiol. B, Biochem. Mol. Biol. 117 (2), 253-257(1997)
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