|Application ||WB, IHC-P, FC, E|
|Other Accession||Q9CQC5, NP_006440|
|Calculated MW||27678 Da|
|Antigen Region||1-30 aa|
|Other Names||Cdc42 effector protein 3, Binder of Rho GTPases 2, MSE55-related Cdc42-binding protein, CDC42EP3, BORG2, CEP3|
|Target/Specificity||This CDC42EP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC42EP3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CDC42EP3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts.|
|Cellular Location||Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton|
|Tissue Location||Highly expressed in the heart and weakly in the brain.|
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Provided below are standard protocols that you may find useful for product applications.
CDC42EP3 is probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. It induces pseudopodia formation in fibroblasts.
Simpson,J.C., et.al., EMBO Rep. 1 (3), 287-292 (2000)
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