|Application ||WB, FC, E|
|Calculated MW||78852 Da|
|Antigen Region||156-184 aa|
|Other Names||Neutral and basic amino acid transport protein rBAT, NBAT, D2h, Solute carrier family 3 member 1, b(0, +)-type amino acid transport protein, SLC3A1, RBAT|
|Target/Specificity||This SLC3A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from the Central region of human SLC3A1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC3A1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the high-affinity, sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney tubule.|
|Cellular Location||Membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed in the brush border membrane in the kidney (at protein level). Predominantly expressed in the kidney, small intestine and pancreas. Weakly expressed in liver|
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Provided below are standard protocols that you may find useful for product applications.
SLC3A1 is a type II membrane glycoprotein which is one of the components of the renal amino acid transporter which transports neutral and basic amino acids in the renal tubule and intestinal tract.
Chabrol,B., et.al., J. Med. Genet. 45 (5), 314-318 (2008)
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