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UBAP1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - UBAP1 Antibody (N-term) AP8828a
    Western blot analysis of UBAP1 Antibody (N-term) (Cat. #AP8828a) in mouse liver, cerebellum tissue lysates (35ug/lane). UBAP1 (arrow) was detected using the purified Pab.
  • IHC-P - UBAP1 Antibody (N-term) AP8828a
    Formalin-fixed and paraffin-embedded human brain tissue reacted with UBAP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - UBAP1 Antibody (N-term) AP8828a
    UBAP1 Antibody (N-term) (Cat. #AP8828a) flow cytometric analysis of HepG2 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZ09
Other Accession NP_057609
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 55084 Da
Antigen Region 6-33 aa
Additional Information
Gene ID 51271
Other Names Ubiquitin-associated protein 1, UBAP-1, Nasopharyngeal carcinoma-associated gene 20 protein, UBAP1
Target/Specificity This UBAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-33 amino acids from the N-terminal region of human UBAP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUBAP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBAP1
Function Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Binds to ubiquitinated cargo proteins and is required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies (MVBs). Plays a role in the proteasomal degradation of ubiquitinated cell-surface proteins, such as EGFR and BST2.
Cellular Location Cytoplasm, cytosol. Endosome. Note=Predominantly cytosolic Recruited to endosomes as part of the ESCRT-I complex
Tissue Location Ubiquitous. Highly expressed in heart, brain, placenta, lung, liver, skeletal muscle and pancreas
Research Areas
Citations (0)

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UBAP1 is a member of the UBA domain family, whose members include proteins having connections to ubiquitin and the ubiquitination pathway. The ubiquitin associated domain is thought to be a non-covalent ubiquitin binding domain consisting of a compact three helix bundle. This particular protein riginates from a gene locus in a refined region on chromosome 9 undergoing loss of heterozygosity in nasopharyngeal carcinoma (NPC). Taking into account its cytogenetic location, this UBA domain family member is being studies as a putative target for mutation in nasopharyngeal carcinomas.


Qian,J.,, J. Cancer Res. Clin. Oncol. 127 (10), 613-618 (2001) Qian,J.,, Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 33 (2), 147-152 (2001)

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$ 295.00
$ 99.00
Cat# AP8828a
(40 western blots)
Availability: In Stock
Bulk Size
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