|Application ||WB, IHC-P, E|
|Calculated MW||25790 Da|
|Antigen Region||218-243 aa|
|Other Names||Dihydropteridine reductase, HDHPR, Quinoid dihydropteridine reductase, QDPR, DHPR|
|Target/Specificity||This QDPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-243 amino acids from the C-terminal region of human QDPR.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||QDPR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||The product of this enzyme, tetrahydrobiopterin (BH-4), is an essential cofactor for phenylalanine, tyrosine, and tryptophan hydroxylases.|
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Provided below are standard protocols that you may find useful for product applications.
QDPR is the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems.
Schnetz-Boutaud,N.C., et.al.,Genes Brain Behav. 8 (8), 753-757 (2009)
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