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ADCY8 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP8858c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP8858c-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
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- Backgrounds
ADCY8 Antibody (Center) - Product info | |
| Application | WB, IHC, FC
|
| Primary Accession | P40145 |
| Other Accession | P40146, P97490 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 140122 Da |
ADCY8 Antibody (Center) - Additional info | |
| Gene ID 114 | |
| Other Names ADCY8; Adenylate cyclase type 8; ATP pyrophosphate-lyase 8; Adenylate cyclase type VIII; Adenylyl cyclase 8; Ca(2+)/calmodulin-activated adenylyl cyclase | |
| Target/Specificity This ADCY8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 952~982 amino acids from the Center region of human ADCY8. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ADCY8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ADCY8 Antibody (Center) - Protein Information | |
| Name ADCY8 | |
| Function This is a membrane-bound, calcium-stimulable adenylyl cyclase. May be involved in learning, in memory and in drug dependence (By similarity) | |
| Cellular Location Membrane; Multi-pass membrane protein. | |
ADCY8 Antibody (Center) - Related products
AP8858c: ADCY8 Antibody (Center)
ADCY8 Antibody (Center) - Application data
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Western blot analysis of ADCY8 Antibody (Center) (Cat. #AP8858c) in HL-60 cell line lysates (35ug/lane). ADCY8 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded mouse brain tissue reacted with ADCY8 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ADCY8 Antibody (Center) (Cat. #AP8858c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
ADCY8 Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
ADCY8 is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase provided by RefSeq].
REFERENCES
Martin,A.C.,et.al., Mol. Pharmacol. 75 (4), 830-842 (2009)
