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FERMT1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FERMT1 Antibody (Center) AP8912c
    FERMT1 Antibody (Center) (Cat. #AP8912c) western blot analysis in Hela,HepG2 cell line lysates (35ug/lane).This demonstrates the FERMT1 antibody detected the FERMT1 protein (arrow).
  • WB - FERMT1 Antibody (Center) AP8912c
    Western blot analysis of FERMT1 Antibody (Center) (Cat. #AP8912c) in mouse stomach tissue lysates (35ug/lane). FERMT1 (arrow) was detected using the purified Pab
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BQL6
Other Accession P59113
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 77437 Da
Antigen Region 268-297 aa
Additional Information
Gene ID 55612
Other Names Fermitin family homolog 1, Kindlerin, Kindlin syndrome protein, Kindlin-1, Unc-112-related protein 1, FERMT1, C20orf42, KIND1, URP1
Target/Specificity This FERMT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 268-297 amino acids from the Central region of human FERMT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFERMT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C20orf42, KIND1, URP1
Function Involved in cell adhesion. Contributes to integrin activation. When coexpressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.
Cellular Location Cytoplasm, cytoskeleton. Cell junction, focal adhesion. Cell projection, ruffle membrane; Peripheral membrane protein; Cytoplasmic side. Note=Constituent of focal adhesions. Localized at the basal aspect of skin keratinocytes, close to the cell membrane. Colocalizes with filamentous actin Upon TGFB1 treatment, it localizes to membrane ruffles
Tissue Location Expressed in brain, skeletal muscle, kidney, colon, adrenal gland, prostate, and placenta. Weakly or not expressed in heart, thymus, spleen, liver, small intestine, bone marrow, lung and peripheral blood leukocytes. Overexpressed in some colon and lung tumors. In skin, it is localized within the epidermis and particularly in basal keratocytes. Not detected in epidermal melanocytes and dermal fibroblasts
Citations (0)

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FERMT1 is a member of the fermitin family, and contains a FERM domain and a pleckstrin homology domain. This protein is involved in integrin signaling and linkage of the actin cytoskeleton to the extracellular matrix.


Goult B.T.,, J. Mol. Biol. 394:944-956(2009).

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$ 295.00
$ 99.00
Cat# AP8912c
(40 western blots)
Availability: In Stock
Bulk Size
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