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CDC5L Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CDC5L Antibody (Center) AP8949c
    Western blot analysis of CDC5L Antibody (Center) (Cat. #AP8949c) in MCF-7 cell line lysates (35ug/lane). CDC5L (arrow) was detected using the purified Pab.
  • FC - CDC5L Antibody (Center) AP8949c
    CDC5L Antibody (Center) (Cat. #AP8949c) flow cytometric analysis of k562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99459
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 92251 Da
Antigen Region 187-213 aa
Additional Information
Gene ID 988
Other Names Cell division cycle 5-like protein, Cdc5-like protein, Pombe cdc5-related protein, CDC5L, KIAA0432, PCDC5RP
Target/Specificity This CDC5L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-213 amino acids from the Central region of human CDC5L.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDC5L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC5L
Synonyms KIAA0432, PCDC5RP
Function DNA-binding protein involved in cell cycle control. May act as a transcription activator. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Cellular Location Nucleus. Nucleus speckle. Cytoplasm. Note=May shuttle between cytoplasm and nucleus.
Tissue Location Ubiquitously expressed in both fetal and adult tissues.
Citations ( 0 )


The protein is a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing.


Grillari,J.,, J. Biol. Chem. 284 (42), 29193-29204 (2009) Zhang,N.,, EMBO Rep. 10 (9), 1029-1035 (2009)

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$ 295.00
$ 99.00
Cat# AP8949c
(40 western blots)
Availability: In Stock
Bulk Size
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