TGOLN2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
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Primary Accession | O43493 |
Other Accession | P19814, Q62314, Q62313 |
Reactivity | Human |
Predicted | Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 45880 Da |
Antigen Region | 399-427 aa |
Gene ID | 10618 |
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Other Names | Trans-Golgi network integral membrane protein 2, TGN38 homolog, TGN46, TGN48, Trans-Golgi network protein TGN51, TGOLN2, TGN46, TGN51 |
Target/Specificity | This TGOLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human TGOLN2. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TGOLN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TGOLN2 (HGNC:15450) |
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Synonyms | TGN46, TGN51 |
Function | May be involved in regulating membrane traffic to and from trans-Golgi network. |
Cellular Location | Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type I membrane protein. Note=Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes |
Tissue Location | Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells |
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Provided below are standard protocols that you may find useful for product applications.
Background
TGOLN2 may be involved in regulating membrane traffic to and from trans-Golgi network.
References
Wu,C., et.al., Proteomics 7 (11), 1775-1785 (2007)
Honing,S., et.al., Mol. Cell 18 (5), 519-531 (2005)
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