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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   FCGR2C Antibody (C-term)   

FCGR2C Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - FCGR2C Antibody (C-term) AP8992b
    Western blot analysis of FCGR2C Antibody (C-term) (Cat. #AP8992b) in mouse brain tissue lysates (35ug/lane).FCGR2C (arrow) was detected using the purified Pab.
  • IHC-P - FCGR2C Antibody (C-term) AP8992b
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with FCGR2C Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • SPECIFICATION
  • CITATIONS: 1
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P31995
Other Accession P12318
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35578 Da
Antigen Region 281-307 aa
Additional Information
Gene ID 9103
Other Names Low affinity immunoglobulin gamma Fc region receptor II-c, IgG Fc receptor II-c, CDw32, Fc-gamma RII-c, Fc-gamma-RIIc, FcRII-c, CD32, FCGR2C, CD32, FCG2, IGFR2
Target/Specificity This FCGR2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 281-307 amino acids from the C-terminal region of human FCGR2C.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFCGR2C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FCGR2C
Synonyms CD32, FCG2, IGFR2
Function Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.
Cellular Location Isoform IIC4: Cytoplasm. Isoform IIC2: Cell membrane; Single-pass type I membrane protein
Tissue Location Isoform IIC1 is detected in monocytes, macrophages, polymorphonuclear cells and natural killer cells
Research Areas
Citations ( 0 )

Background

FCGR2C is the receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. It is involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells.

References

Metes D., et.al., Blood 91:2369-2380(1998).
Stuart S.G.,et.al., EMBO J. 8:3657-3666(1989).

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$ 295.00
$ 99.00
Cat# AP8992b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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