|Application ||WB, IHC-P, FC, E|
|Calculated MW||53765 Da|
|Antigen Region||337-365 aa|
|Other Names||EGF-like repeat and discoidin I-like domain-containing protein 3, Developmentally-regulated endothelial cell locus 1 protein, Integrin-binding protein DEL1, EDIL3, DEL1|
|Target/Specificity||This EDIL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human EDIL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EDIL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Promotes adhesion of endothelial cells through interaction with the alpha-v/beta-3 integrin receptor. Inhibits formation of vascular-like structures. May be involved in regulation of vascular morphogenesis of remodeling in embryonic development.|
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Provided below are standard protocols that you may find useful for product applications.
EDIL3 is an integrin ligand. It plays an important role in mediating angiogenesis and may be important in vessel wall remodeling and development. It also influences endothelial cell behavior.
Aoka,Y., et.al., Microvasc. Res. 64 (1), 148-161 (2002)
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