|Application ||WB, IHC-P, FC, E|
|Calculated MW||144756 Da|
|Antigen Region||112-139 aa|
|Other Names||Protein broad-minded, TBC1 domain family member 32, TBC1D32, BROMI, C6orf170, C6orf171|
|Target/Specificity||This C6orf170 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 112-139 amino acids from the N-terminal region of human C6orf170.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C6orf170 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BROMI, C6orf170, C6orf171|
|Function||Required for high-level Shh responses in the developing neural tube. Together with CDK20, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to Shh signaling (By similarity).|
|Cellular Location||Cytoplasm. Cell projection, cilium|
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Provided below are standard protocols that you may find useful for product applications.
Ota T., et.al., Nat. Genet. 36:40-45(2004).
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