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>   home   >   Products   >   Primary Antibodies   >   SPG20 Antibody (N-term)   

SPG20 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SPG20 Antibody (N-term) AP9040a
    Western blot analysis of SPG20 Antibody (N-term) (Cat. #AP9040a) in NCI-H460 cell line lysates (35ug/lane). SPG20 (arrow) was detected using the purified Pab.
  • IHC-P - SPG20 Antibody (N-term) AP9040a
    Formalin-fixed and paraffin-embedded human brain tissue reacted with SPG20 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - SPG20 Antibody (N-term) AP9040a
    SPG20 Antibody (N-term) (Cat. #AP9040a) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8N0X7
Other Accession Q8R1X6, A0JNJ3
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 72833 Da
Antigen Region 18-45 aa
Additional Information
Gene ID 23111
Other Names Spartin, Spastic paraplegia 20 protein, Trans-activated by hepatitis C virus core protein 1, SPG20, KIAA0610, TAHCCP1
Target/Specificity This SPG20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 18-45 amino acids from the N-terminal region of human SPG20.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSPG20 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SPG20
Synonyms KIAA0610, TAHCCP1
Function May be implicated in endosomal trafficking, or microtubule dynamics, or both.
Cellular Location Cytoplasm. Note=Transiently associated with endosomes
Tissue Location Ubiquitously expressed, with highest levels of expression detected in adipose tissue
Citations (0)

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SPG20 is a protein containing a MIT (Microtubule Interacting and Trafficking molecule) domain, and is implicated in regulating endosomal trafficking and mitochondria function. The protein localizes to mitochondria and partially co-localizes with microtubules. Stimulation with epidermal growth factor (EGF) results in protein translocation to the plasma membrane, and the protein functions in the degradation and intracellular trafficking of EGF receptor.


Milewska,M.,, J. Neurochem. 111 (4), 1022-1030 (2009);
Edwards,T.L.,, Biochem. J. 423 (1), 31-39 (2009).

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$ 295.00
$ 99.00
Cat# AP9040a
(40 western blots)
Availability: In Stock
Bulk Size
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