SDS Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | P20132 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 34625 Da |
Antigen Region | 1-30 aa |
Gene ID | 10993 |
---|---|
Other Names | L-serine dehydratase/L-threonine deaminase, SDH, L-serine deaminase, L-threonine dehydratase, TDH, SDS, SDH |
Target/Specificity | This SDS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SDS. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SDS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SDS |
---|---|
Synonyms | SDH |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SDS encodes one of three enzymes that are involved in metabolizing serine and glycine. L-serine dehydratase converts L-serine to pyruvate and ammonia and requires pyridoxal phosphate as a cofactor. The encoded protein can also metabolize threonine to NH4+ and 2-ketobutyrate. The encoded protein is found predominantly in the liver.
References
Yamada,T., et.al., Biochim. Biophys. Acta 1780 (5), 809-818 (2008)
Szaflik,J.P., et.al., Exp. Eye Res. 86 (4), 647-652 (2008)
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