|Application ||WB, IHC-P, FC, E|
|Calculated MW||104749 Da|
|Antigen Region||43-72 aa|
|Other Names||Exostosin-like 3, EXT-related protein 1, Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase, Hereditary multiple exostoses gene isolog, Multiple exostosis-like protein 3, Putative tumor suppressor protein EXTL3, EXTL3, EXTL1L, EXTR1, KIAA0519|
|Target/Specificity||This EXTL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 43-72 amino acids from the N-terminal region of human EXTL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EXTL3 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Glycosyltransferase which regulates the biosynthesis of heparan sulfate (HS). Important for both skeletal development and hematopoiesis, through the formation of HS proteoglycans (HSPGs) (PubMed:28132690, PubMed:28148688). Required for the function of REG3A in regulating keratinocyte proliferation and differentiation (PubMed:22727489).|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus|
|Tissue Location||Ubiquitous. Expressed in keratinocytes.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
EXTL3 is probable glycosyltransferase.
Kaidonis,X., et.al., Eur. J. Hum. Genet. 18 (2), 194-199 (2010)
Pata,G., et.al., J Surg Oncol 100 (6), 520-522 (2009)
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