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RABAC1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 2
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9UI14 |
| Other Accession | Q52NJ0 and Q9Z0S9, Q52NJ0 |
| Reactivity | Human, Mouse |
| Predicted | Pig |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 20648 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 10567 |
|---|---|
| Other Names | Prenylated Rab acceptor protein 1, PRA1 family protein 1, RABAC1, PRA1, PRAF1 |
| Target/Specificity | This RABAC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human RABAC1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | RABAC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | RABAC1 |
|---|---|
| Synonyms | PRA1, PRAF1 |
| Function | General Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:O35394}; Multi-pass membrane protein. Cytoplasm {ECO:0000250|UniProtKB:O35394}. Golgi apparatus {ECO:0000250|UniProtKB:O35394}. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle {ECO:0000250|UniProtKB:O35394}. Note=According to some authors, it is an integral membrane protein, while others showed that it is cytoplasmic and membrane-associated to Golgi and synaptic vesicles. {ECO:0000250|UniProtKB:O35394} |
| Tissue Location | Ubiquitous. Strongest expression found in placenta, pituitary gland, kidney, lung and stomach |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
RABAC1 is general Rab protein regulator required for vesicle formation from the Golgi complex. May control vesicle docking and fusion by mediating the action of Rab GTPases to the SNARE complexes. In addition it inhibits the removal of Rab GTPases from the membrane by GDI.
References
Venkatesan,K., et.al., Nat. Methods 6 (1), 83-90 (2009)
Kim,J.T., et.al., Biochem. Biophys. Res. Commun. 349 (1), 200-208 (2006)
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$ 365.00
$ 140.00
Cat# AP9049a
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