|Application ||WB, FC, IF, E|
|Calculated MW||149548 Da|
|Antigen Region||1247-1276 aa|
|Other Names||Histone demethylase UTY, 11411-, Ubiquitously-transcribed TPR protein on the Y chromosome, Ubiquitously-transcribed Y chromosome tetratricopeptide repeat protein, UTY, KDM6C|
|Target/Specificity||This UTY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1247-1276 amino acids from the C-terminal region of human UTY.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||UTY Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Male-specific histone demethylase that catalyzes trimethylated 'Lys-27' (H3K27me3) demethylation in histone H3. Has relatively low lysine demethylase activity.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
UTY encodes a protein containing tetratricopeptide repeats which are thought to be involved in protein-protein interactions. This protein is a minor histocompatibility antigen which may induce graft rejection of male stem cell grafts.
Russo,P., et.al., Arterioscler. Thromb. Vasc. Biol. 28 (8), 1569-1574 (2008)
Gerrard,D.T. et.al., Mol. Biol. Evol. 22 (6), 1423-1432 (2005)
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