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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   DUSP2 Antibody (C-term)   

DUSP2 Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DUSP2 Antibody (C-term) AP9084B
    Western blot analysis of DUSP2 Antibody (C-term) (Cat. #AP9084b) in mouse liver tissue lysates (35ug/lane). DUSP2 (arrow) was detected using the purified Pab.
  • FC - DUSP2 Antibody (C-term) AP9084B
    DUSP2 Antibody (C-term) (Cat. #AP9084b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q05923
Other Accession Q05922
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 34400 Da
Antigen Region 262-290 aa
Additional Information
Gene ID 1844
Other Names Dual specificity protein phosphatase 2, Dual specificity protein phosphatase PAC-1, DUSP2, PAC1
Target/Specificity This DUSP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 262-290 amino acids from the C-terminal region of human DUSP2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDUSP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DUSP2
Synonyms PAC1
Function Regulates mitogenic signal transduction by dephosphorylating both Thr and Tyr residues on MAP kinases ERK1 and ERK2.
Cellular Location Nucleus.
Tissue Location Expressed in hematopoietic tissues.
Research Areas
Citations (0)

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DUSP2 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.


Caunt,C.J.,, J. Biol. Chem. 283 (10), 6241-6252 (2008)
Baranyai,R.,, Neuropsychobiology 57 (3), 146-150 (2008)

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Cat# AP9084B
(40 western blots)
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