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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   LOX Antibody (Center)   

LOX Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LOX Antibody (Center) AP9127c
    Western blot analysis of LOX Antibody (Center) (Cat. #AP9127c) in MDA-MB468 cell line lysates (35ug/lane). LOX (arrow) was detected using the purified Pab.
  • FC - LOX Antibody (Center) AP9127c
    LOX Antibody (Center) (Cat. #AP9127c) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P28300
Other Accession P16636, P45845, P28301
Reactivity Human
Predicted Mouse, Pig, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46944 Da
Antigen Region 234-260 aa
Additional Information
Gene ID 4015
Other Names Protein-lysine 6-oxidase, Lysyl oxidase, LOX
Target/Specificity This LOX antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 234-260 amino acids from the Central region of human LOX.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLOX Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LOX
Function Responsible for the post-translational oxidative deamination of peptidyl lysine residues in precursors to fibrous collagen and elastin. In addition to cross-linking of extracellular matrix proteins, may have a direct role in tumor suppression.
Cellular Location Secreted, extracellular space.
Tissue Location Heart, placenta, skeletal muscle, kidney, lung and pancreas.
Research Areas
Citations (0)

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LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression.


Mariani,T.J.,, Matrix 12 (3), 242-248 (1992)

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Cat# AP9127c
(40 western blots)
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