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MUTYH Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MUTYH Antibody (Center) AP9161c
    Western blot analysis of MUTYH Antibody (Center) (Cat. #AP9161c) in mouse lung tissue lysates (35ug/lane). MUTYH (arrow) was detected using the purified Pab.
  • FC - MUTYH Antibody (Center) AP9161c
    MUTYH Antibody (Center) (Cat. #AP9161c) flow cytometric analysis of NCI-H460 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • IF - MUTYH Antibody (Center) AP9161c
    Confocal immunofluorescent analysis of MUTYH Antibody (Center) (Cat. #AP9161c) with Hela cell followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UIF7
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60069 Da
Antigen Region 341-367 aa
Additional Information
Gene ID 4595
Other Names A/G-specific adenine DNA glycosylase, 322-, MutY homolog, hMYH, MUTYH, MYH
Target/Specificity This MUTYH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-367 amino acids from the Central region of human MUTYH.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMUTYH Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms MYH
Function Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2- OH-A DNA glycosylase activities.
Cellular Location Nucleus.
Citations (0)

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MYH is the eukaryotic homolog to the E. coli protein MutY. It was first identified in HeLa cells and nicks DNA replication errors, specifically A/G mismatches. MYH is involved in oxidative DNA damage repair. It initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. It possesses both adenine and 2-OH-A DNA glycosylase activities.


Kim C.J.,, Oncogene 23:6820-6822(2004).
Isidro G.,, Hum. Mutat. 24:353-354(2004).
Sieber O.M.,, N. Engl. J. Med. 348:791-799(2003).

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$ 295.00
$ 99.00
Cat# AP9161c
(40 western blots)
Availability: In Stock
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