AFMID Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, WB, E |
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Primary Accession | Q63HM1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33992 Da |
Antigen Region | 57-83 aa |
Gene ID | 125061 |
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Other Names | Kynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_03014}, KFA {ECO:0000255|HAMAP-Rule:MF_03014}, KFase {ECO:0000255|HAMAP-Rule:MF_03014}, 3519 {ECO:0000255|HAMAP-Rule:MF_03014}, Arylformamidase {ECO:0000255|HAMAP-Rule:MF_03014}, N-formylkynurenine formamidase {ECO:0000255|HAMAP-Rule:MF_03014}, FKF {ECO:0000255|HAMAP-Rule:MF_03014}, AFMID {ECO:0000255|HAMAP-Rule:MF_03014} |
Target/Specificity | This AFMID antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 57-83 amino acids from the N-terminal region of human AFMID. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | AFMID Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AFMID {ECO:0000255|HAMAP-Rule:MF_03014} |
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Function | Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. |
Cellular Location | Cytoplasm, cytosol {ECO:0000255|HAMAP- Rule:MF_03014}. Nucleus {ECO:0000255|HAMAP-Rule:MF_03014} Note=Predominantly cytosolic. Some fraction is nuclear {ECO:0000255|HAMAP-Rule:MF_03014} |
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Provided below are standard protocols that you may find useful for product applications.
References
Magni,G., et.al., Cell. Mol. Life Sci. 61 (1), 19-34 (2004)
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