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DSTN Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DSTN Antibody (Center) AP9189c
    Western blot analysis of DSTN Antibody (Center) (Cat. #AP9189c) in MCF-7 cell line lysates (35ug/lane). DSTN (arrow) was detected using the purified Pab.
  • IHC-P - DSTN Antibody (Center) AP9189c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with DSTN Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - DSTN Antibody (Center) AP9189c
    DSTN Antibody (Center) (Cat. #AP9189c) flow cytometry analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • WB - DSTN Antibody (Center) AP9189c
    Western blot analysis of DSTN (arrow) using rabbit polyclonal DSTN Antibody (Center) (Cat. #AP9189c). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the DSTN gene.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P60981
Other Accession Q7M0E3, P60982, Q9R0P5, Q5E9D5
Reactivity Human
Predicted Bovine, Mouse, Pig, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 18506 Da
Antigen Region 70-98 aa
Additional Information
Gene ID 11034
Other Names Destrin, Actin-depolymerizing factor, ADF, DSTN, ACTDP, DSN
Target/Specificity This DSTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the Central region of human DSTN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDSTN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms ACTDP, DSN
Function Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH- independent manner.
Tissue Location Widely distributed in various tissues.
Research Areas
Citations (0)

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DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This protein encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).


Estornes,Y.,, Int. J. Cancer 121 (10), 2162-2171 (2007)
Mannherz,H.G.,, J. Mol. Biol. 366 (3), 745-755 (2007)

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$ 295.00
$ 99.00
Cat# AP9189c
(40 western blots)
Availability: In Stock
Bulk Size
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