|Application ||WB, IHC-P, FC, E|
|Other Accession||Q7M0E3, P60982, Q9R0P5, Q5E9D5|
|Predicted||Bovine, Mouse, Pig, Rat|
|Calculated MW||18506 Da|
|Antigen Region||70-98 aa|
|Other Names||Destrin, Actin-depolymerizing factor, ADF, DSTN, ACTDP, DSN|
|Target/Specificity||This DSTN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 70-98 amino acids from the Central region of human DSTN.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DSTN Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Actin-depolymerizing protein. Severs actin filaments (F- actin) and binds to actin monomers (G-actin). Acts in a pH- independent manner.|
|Tissue Location||Widely distributed in various tissues.|
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Provided below are standard protocols that you may find useful for product applications.
DSTN belongs to the actin-binding proteins ADF family. This family of proteins is responsible for enhancing the turnover rate of actin in vivo. This protein encodes the actin depolymerizing protein that severs actin filaments (F-actin) and binds to actin monomers (G-actin).
Estornes,Y., et.al., Int. J. Cancer 121 (10), 2162-2171 (2007)
Mannherz,H.G., et.al., J. Mol. Biol. 366 (3), 745-755 (2007)
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