ADH6 Antibody (Center)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| FC, IHC-P, WB, E |
---|---|
Primary Accession | P28332 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 39073 Da |
Antigen Region | 209-240 aa |
Gene ID | 130 |
---|---|
Other Names | Alcohol dehydrogenase 6, ADH6 |
Target/Specificity | This ADH6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 209-240 amino acids from the Central region of human ADH6. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ADH6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ADH6 |
---|---|
Function | Alcohol dehydrogenase (PubMed:1755855). Catalyzes the NAD- dependent oxidation of primary alcohols to the corresponding aldehydes (PubMed:1755855). Oxidizes secondary alcohols to the corresponding ketones (By similarity). |
Cellular Location | Cytoplasm. |
Tissue Location | Stomach and liver.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ADH6 encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site.
References
Cui,R., et.al., Gastroenterology 137 (5), 1768-1775 (2009)
Saito,A., et.al., J. Hum. Genet. 54 (6), 317-323 (2009)
Tabakoff,B., et.al., BMC Biol. 7, 70 (2009)
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