|Application ||WB, E|
|Calculated MW||36490 Da|
|Antigen Region||94-119 aa|
|Other Names||Forkhead box protein L1, Forkhead-related protein FKHL11, Forkhead-related transcription factor 7, FREAC-7, FOXL1, FKHL11, FREAC7|
|Target/Specificity||This FOXL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-119 amino acids from the Central region of human FOXL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Precautions||FOXL1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
The forkhead domain is a 100-amino acid monomeric DNA binding motif originally identified as a region of homology between the Drosophila forkhead protein and rat HNF3. Pierrou et al. (1994) identified 7 human genes containing forkhead domains and designated them forkhead related activators (FREAC) 1 through 7.
Rivadeneira,F., et.al., Nat. Genet. 41 (11), 1199-1206 (2009)
Ferrell,R.E., et.al., Lymphat Res Biol 6 (2), 69-76 (2008)
Hassel,S., et.al., Proteomics 4 (5), 1346-1358 (2004)
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