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MALD2 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - MALD2 Antibody (C-term) AP9219b
    Western blot analysis of MALD2 Antibody (C-term) (Cat. #AP9219b) in WiDr, MDA-MB231 cell line lysates (35ug/lane). MALD2 (arrow) was detected using the purified Pab.
    detail
  • IHC-P - MALD2 Antibody (C-term) AP9219b
    Formalin-fixed and paraffin-embedded human brain tissue reacted with MALD2 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
IHC-P, WB, E
Primary Accession Q8N4S9
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 64168 Da
Antigen Region 386-415 aa
Additional Information
Gene ID 153562
Other Names MARVEL domain-containing protein 2, Tricellulin, MARVELD2, TRIC
Target/Specificity This MALD2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-415 amino acids from the C-terminal region of human MALD2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMALD2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MARVELD2 (HGNC:26401)
Synonyms TRIC
Function Plays a role in the formation of tricellular tight junctions and of epithelial barriers (By similarity). Required for normal hearing via its role in the separation of the endolymphatic and perilymphatic spaces of the organ of Corti in the inner ear, and for normal survival of hair cells in the organ of Corti (PubMed:17186462).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, tight junction. Note=Located at tricellular contacts.
Research Areas
Citations (0)
citation

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Background

MALD2 plays a role in the formation of the epithelial barriers. The separation of the endolymphatic and perilymphatic spaces of the organ of Corti from one another by epithelial barriers is required for normal hearing.

References

Tam,S., et.al., Nat. Struct. Mol. Biol. 16 (12), 1279-1285 (2009)
Krug,S.M., et.al., Mol. Biol. Cell 20 (16), 3713-3724 (2009)

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$ 365.00
$ 140.00
Cat# AP9219b
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